Oct 29, 2014 smartphones are revolutionizing approaches to wellbeing investment. The intervention commenced in march 2014 with followup until september 2016. We assessed the effects of individualised diets in patients with ibs guided by a leucocyte activation test. A randomised, doubleblind, placebo controlled, parallel group trial. Objective to investigate whether an early rehabilitation intervention initiated during acute admission for exacerbations of chronic respiratory disease reduces the risk of readmission over 12 months and ameliorates the negative effects of the episode on physical performance and health status. This study aims to investigate the effect of a smartphonebased home service delivery care assessment platform of cr capcr on cr use and health outcomes compared with a traditional, centrebased programme tcr in postmi patients. The effect of phosphatidylserine administration on memory. A randomised controlled trial of azithromycin therapy in.
In this trial, we aimed at evaluating the efficacy and safety of mesalazine in patients with ibs. Exercise is a promising strategy for combating cognitive decline by improving brain structure and function. Effects of needsbased patient education on selfefficacy and. Patientreported improvements in health are maintained 2.
Methods patients with ra were enrolled into this multicentre, singleblind, parallelgroup, pragmatic randomised controlled trial. The intervention consisted of weekly supervised group sessions of progressive balance training offered in community based premises for two years, supplemented by. This randomised controlled trial will investigate the efficacy of a progressive physiotherapistsupervised rehabilitation program taklaodonnell protocol in improving healthrelated quality of life, physical function and symptoms in individuals undergoing arthroscopic management of femoroacetabular impingement. Randomized controlled trials rcts are the gold standard for evaluating treatment outcomes.
Preliminary evidence indicates that foot orthoses improve symptoms of individuals with achilles tendinopathy. The aim of this study was to evaluate the effectiveness of workfocused cognitivebehavioural therapy cbt and individual job support for people struggling with work participation due to cmds. Jun 19, 2014 to evaluate a multistrain, highdose probiotic in the prevention of eczema. Methods a randomised controlled multicentre trial rct including 1193 participants was conducted. Ginkgo biloba extract improved cognitive and neurological.
Workfocused cognitivebehavioural therapy and individual. Nct01659736 to investigate the efficacy and neural correlates of rtms in gad. Design we conducted a phase 3, multicentre, tertiary setting, randomised, doubleblind, placebocontrolled trial in patients with rome iii confirmed ibs. A clinical trial is a method for comparing objectively, by a prospective study. Purpose to describe the imaging standards, grading protocol and baseline characteristics of polypoidal choroidal vasculopathy pcv from the everest study. A multicentre parallel group randomised controlled trial study design was used. The heads study is a two armed pragmatic randomised controlled trial nested in a prospective cohort study fig 1. Results over the period of the study, 76 unique indications were granted without rct results 44 by the ema and 60 by the fda, demonstrating that a substantial number of treatments reach the market without undergoing an rct. The effect of rate of weight loss on longterm weight.
Methods this is a parallelgroup, doubleblind, randomised controlled trial of 58 adults with ibs seen at an academic health centre. Randomized controlled trials rcts are the hallmark of evidencebased medicine and form the basis for translating research data into clinical. Almost all 195 98% patients were in canadian cardiovascular society class ii or iii at enrolment. A cluster randomised trial of cloth masks compared with. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. A randomized controlled trial or randomized control trial. Homeopathys advocates tend to deny the worth of randomised controlled trials rcts or overinterpret their findings, whilst its critics dispute the therapys scientific rationale and the existence of any positive findings in the research literature. Randomised controlled trials national council for osteopathic. Helmet therapy in infants with positional skull deformation. Effectiveness of customised foot orthoses for achilles. This was a randomised, controlled and singleblinded trial that included an intervention of an aerobic training programme. There was best practice, randomised controlled trial, evidence available to the dietary committees, which was not considered and should have been. Open access research a cluster randomised trial of cloth. A randomized controlled trial rct is a way of doing impact evaluation in which the population receiving the programme or policy intervention is chosen at random from the eligible population, and a control group is also chosen at random from the same eligible population.
We tested the hypothesis that the outcome of an individualised homeopathic treatment approach using homeopathic medicines is distinguishable from that of placebos. Setting an acute cardiorespiratory unit in a teaching. We devised a randomised controlled trial to evaluate the effectiveness and efficiency of an intervention based on case management care for frequent emergency department users. The study was performed between two medical visits, and during the intervention period, the pharmacotherapy was maintained. These findings are not consistent with present dietary guidelines which recommend gradual over rapid weight loss, based on the belief that rapid weight loss is more quickly regained. Workfocused cognitivebehavioural therapy and individual job. Background we conducted a placebocontrolled trial of azithromycin therapy in bronchiolitis obliterans syndrome bos post lung transplantation. Design steppedwedge cluster randomised controlled trial. Randomized controlled trials rcts unicef office of research. Methods medline, embase, web of knowledge and the cochrane central register of controlled trials were searched for doubleblinded randomised controlled trials of ivabradine with a minimum followup period of 4 weeks. There were no substantial differences in the baseline demographics of the two groups.
May 2014 and the meeting of the society for biological psychiatry, new york, may 2014. The main finding of this randomised controlled trial was that, in patients with copd, a programme of advice alone had no impact on physical activity, whereas a pedometerbased programme produced significant increases in daily step count which were accompanied by clinically significant improvements in health status. Cluster randomised controlled trial evaluating the. Original article vedolizumab affects antibody responses to. The aim of this study was to determine the efficacy of cloth masks compared with medical masks in hcws working in highrisk hospital wards, against the prevention of respiratory infections. Cloth masks have been used in west africa during the ebola outbreak in 2014, due to shortages of ppe, personal communication, m. Smartphones are revolutionizing approaches to wellbeing investment. The trial started on the 3 march 2011, with rolling recruitment undertaken between 3 march 2011 and 10 march 2011. The clinical and costeffectiveness of brief advice for. Oct 15, 2014 the rate of weight loss does not affect the proportion of weight regained within 144 weeks. Intervention patients received mas, which included a consultation with the pharmacist. Objectives the musician study has previously shown shortterm benefit but only marginal costeffectiveness for two nonpharmacological interventions for chronic widespread pain cwp. Worldwide demand for online access to the information resource was high. Specifically, aerobic training at improved spatial memory and hippocampal volume in healthy community.
Pdf on feb 11, 2015, leonardo silva roever borges and others published critical appraisal of randomised controlled trials find, read and cite all the research you need on researchgate. Objective lowgrade intestinal inflammation plays a role in the pathophysiology of ibs. Results from the heads non randomised controlled trial will be presented in the near future and might provide additional evidence to set next to the results of the present randomised controlled trial. Objective cardiac rehabilitation cr is pivotal in preventing recurring events of myocardial infarction mi. In a randomised control trial rct different units are randomly assigned to. Pointofcare ultrasonography in patients admitted with. Effect of handson interprofessional simulation training for. A study in which a number of similar people are randomly assigned to 2 or more groups to test a specific drug, treatment or other intervention. Aerobic exercise increases hippocampal volume in older women. One hundred and forty participants aged 1855 years with midportion achilles tendinopathy were randomised to receive eccentric calf muscle exercises with either customised foot orthoses intervention group or sham foot. Patients were randomly assigned to either mesalazine. This is the first randomised controlled trial clinicaltrials.
All images were graded using standardised, calibrated equipment by. A cluster randomised trial of cloth masks compared with medical masks in healthcare workers. Aug 17, 2015 we searched pubmed, psychinfo, the cumulative index to nursing and allied health literature cinahl, the web of science, the cochrane library and the current controlled trials register for articles published between january 2010 and may 2014. Pdf critical appraisal of randomised controlled trials. Peripheral venous blood was analysed using a leucocyte activation test.
A cluster randomised trial of medical and cloth mask use for hcws was conducted in 14 hospitals in hanoi, vietnam. Original article vedolizumab affects antibody responses. This prospective, parallelgroup, singleblind randomised controlled trial, with a superiority design, was done at the medical emergency department at odense university hospital, odense, denmark. A pilot, open labelled, randomised controlled trial of. Repetitive transcranial magnetic stimulation for generalised.
To evaluate a multistrain, highdose probiotic in the prevention of eczema. The nature of the research evidence in homeopathy is a matter of ongoing scientific debate. A brief description a randomized controlled trial rct is a way of doing impact evaluation in which the population receiving the programme or policy intervention is chosen at random from the eligible population, and a control group. Effects of vedolizumab on immune responses to parenterally or enterally administered antigens were investigated. The distinction between randomized clinical trials rcts and. Future research should determine the effects of helmet therapy in very severe skull deformation. A randomised, doubleblind, placebocontrolled, parallel group trial. Background mild cognitive impairment mci is a wellrecognised risk factor for dementia and represents a vital opportunity for intervening. Percutaneous coronary intervention in stable angina orbita. A clusterrandomised trial of medical and cloth mask use for hcws was conducted in 14 hospitals in hanoi, vietnam.
A randomised controlled clinical trial compared the efficacy of iui and ivf in a tertiary fertility centre isrctn28780587. Methods a clusterrandomised trial of medical and cloth mask use for hcws was conducted in 14 hospitals in hanoi, vietnam. Randomised controlled trials and populationbased observational research. Evidencebased practice tutorial randomised controlled. Methods this is a parallelgroup, doubleblind, randomised controlled trial of 58 adults with ibs seen at an academic health centre in northeast usa. We considered stepped wedge randomised controlled trials in all fields of research. Acupuncture in medicine aims to promote the scientific understanding of acupuncture and related treatments by publishing scientific investigations of their effectiveness and modes of action as well as articles on their use in health services and clinical practice. The effect of phosphatidylserine administration on memory and. Pdf a randomised controlled trial to compare the clinical and cost. Pdf pedometers to enhance physical activity in copd. Aerobic exercise increases hippocampal volume in older. Design we conducted a phase 3, multicentre, tertiary setting, randomised, doubleblind, placebo controlled trial in patients with rome iii confirmed ibs.
Randomised placebocontrolled trials of individualised. Objectives to examine the clinical and costeffectiveness of brief advice for excessive alcohol consumption among people who attend sexual health clinics. Methods we compared azithromycin 250 mg alternate days, 12 weeks with placebo. Study design this is an open randomised controlled. Cluster randomised controlled trial evaluating the clinical. The emergency department has about 58 800 visits per year, and 12 000 of these result in admission to the emergency department. Pdf on jan 1, 2005, harald o stolberg and others published randomized controlled trials find, read and cite all the research you need on researchgate. Background we conducted a placebo controlled trial of azithromycin therapy in bronchiolitis obliterans syndrome bos post lung transplantation. Rct is a type of scientific often medical experiment that aims to reduce certain sources of bias when testing the effectiveness of new treatments.
Acupuncture in medicine uses the western understanding of neurophysiology and. Rcts reporting results of marginal clinical significance to the selected. A randomised controlled trial of rosuvastatin for the prevention of aminoglycosideinduced kidney toxicity in children with cystic fibrosis. Efficacy of a physiotherapy rehabilitation program for. Repetitive transcranial magnetic stimulation for generalised anxiety disorder. Mas pharmacists were trained in clinical pathways and communication systems mutually agreed with general practitioners and received monthly support. Participants were followed during the same calendar time for 4 weeks of facemasks use. Tacrolimus versus mycophenolate mofetil for induction therapy. The effect of phosphatidylserine administration on memory and symptoms of attention. It was established, post randomisation that two did not. Randomised controlled trial of mesalazine in ibs gut. Antenatal clinics, research clinic, children at home.
A randomized clinical trial rct is conducted to compare 2 or. Available formats pdf please select a format to send. Capcr, delivered in participants homes, included health and exercise monitoring, motivational and educational material delivery, and. A randomised controlled trial of rosuvastatin for the. Due to its potential to concurrently improve workrelated wellbeing wrw and job performance, occupational stakeholders are becoming increasingly interested in the applications of meditation. The present study conducted the first randomized controlled trial to assess the effects of meditation on outcomes relating to both wrw and job performance.
A randomized controlled trial rct is a way of doing impact evaluation in which the population receiving. Objective to quantify any risk of atrial fibrillation af associated with ivabradine treatment by metaanalysis of clinical trial data. Tacrolimus versus mycophenolate mofetil for induction. One group the experimental group has the intervention being tested, the other the comparison or control. Researchers assessed the effectiveness of an exercise programme in reducing injurious falls among women at increased risk of falls and injuries. Randomized controlled trials a matter of design ncbi. The feasibility of conducting a definitive randomised controlled trial rct evaluating the clinical effectiveness and costeffectiveness of scoliosisspecific exercises sses for adolescent. Effect of handson interprofessional simulation training. A pilot, open labelled, randomised controlled trial of hypertonic saline nasal irrigation and gargling for the common cold skip to main. Design in this randomised, doubleblind, placebocontrolled, phase i trial, healthy participants received a. Hirayama department of early childhood education and care, kurashiki city college, okayama, japan.
Methods twoarm, parallel group, assessor blind, pragmatic, randomised controlled trial. Methods we conducted a multicentre, prospective, randomised, open label, blinded, controlled clinical trial enrollingpatients with an onset of acute stroke within 7 days from five hospitals in china. The effect of rate of weight loss on longterm weight management. Atrial fibrillation associated with ivabradine treatment. We searched pubmed, psychinfo, the cumulative index to nursing and allied health literature cinahl, the web of science, the cochrane library and the current controlled trials register for articles published between january 2010 and may 2014. The majority was for haematological malignancies 34, with the next most common areas being oncology 15. The followup study was designed to catch all infants eligible for helmet therapy after a period of paediatric physiotherapy or a. The rate of weight loss does not affect the proportion of weight regained within 144 weeks. A pilot randomised, doubleblind, sham controlled trial volume 209 issue 3 gretchen j. Multicentre, randomised clinical trial of paediatric concussion assessment of rest and exertion pedcare. Correspondence to dr chi chiu mok, department of medicine, tuen mun hospital, hong kong. Effects of needsbased patient education on selfefficacy. Methods in this unblinded randomised controlled trial, postmi patients were randomised to tcr n60.
Smartphonebased home care model improved use of cardiac. Purpose to evaluate the efficacy and safety of ginkgo biloba extract gbe in acute ischaemic stroke and its impact on the recurrence of vascular events. One hundred and forty participants aged 1855 years with midportion achilles tendinopathy were randomised to receive eccentric calf muscle exercises with either customised foot orthoses intervention group or sham foot orthoses control group. Percutaneous coronary intervention in stable angina. We searched pubmed on july 7, 2014, for randomised clinical trials published in english assessing the rate of weight loss on weight maintenance. Our glossary excludes specific clinical and medical terms. Primary outcome measures were fetal heart positive pregnancy rate and cost per live birth. A randomised controlled trial article pdf available in european respiratory journal 452 september 2014 with 206 reads how we measure reads. Randomised controlled trials and populationbased observational. Thus, using neuroimaging data from a proofofconcept singleblinded randomised controlled trial nct00958867 of exercise,12, we conducted a secondary analysis to assess. Efficacy of individualised diets in patients with irritable. Three additional units were included in a supplementary analysis to assess the effect across scotland.
Randomized controlled trials and real life studies. The results of the present metaanalysis support the hypothesis that the available rcts did not support the introduction of dietary fat recommendations in order to reduce chd risk or related mortality. Background patients with irritable bowel syndrome ibs are often placed on diets guided by food intolerance assays, although these have not been validated. We wished to determine their longterm effectiveness and costeffectiveness.
Author links open overlay panel katrina purcell bsc a priya sumithran phd a luke a prendergast phd a b celestine j bouniu. The aim of this study was to evaluate the effects of needsbased patient education on selfefficacy, health outcomes and patient knowledge in people with rheumatoid arthritis ra. Evidence from placebocontrolled randomised controlled trials shows that single antianginal therapies provide improvements in exercise time of 4855 s. This investigation explored the viability of delivering a positive psychological intervention in application format to authentic happiness seekers. An early rehabilitation intervention to enhance recovery. Those seeking greater happiness can engage with thousands of downloadable selfhelp applications instantly, yet their effectiveness remains largely unknown. Case management for frequent users of the emergency. The aim of the intervention is to reduce such patients emergency department use, to improve their quality of life, and to reduce costs consequent on frequent use. This investigation explored the viability of delivering a positive psychological intervention in application format to authentic happiness. Methods in a prospective, multicentre study, confocal scanning laser ophthalmoscope indocyanine green angiography icga was performed using a standardised imaging protocol. Bronchiectasis, exacerbation, selfmanagement, education, information, randomised controlled trial, feasibility.
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